#WeCATS - Thursday 25th June 2015 8pm (GMT Standard Time) #WeCATS: Mindfulness for recurrent depression (Lancet RCT)

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Hosted by WeNurses using #WeCATS

#WeCATS discussions are "Critical Appraisal Twitter Sessions" & are a @UKCochraneCentr @Mental_Elf @CASPUK & @WeNurses collaboration. 


Hello and welcome to our first #WeCATS topic - to find our more about #WeCATS please see our blog "Critical Appraisal CATS ??


It's important to say that you don't have to be a critical appraisal expert to join in #WeCATS but you do have to had read the paper .... sooooo here is the link to our first #WeCATS paper:


Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial (Kuyken et al 2015) 

Open acess paper Via @TheLancet






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For a full critical appraisal of this paper please see The Mental Elf 



Questions And Answer Summary














































































#JargonBin 

 A few terms were thrown into the jargon bin during this discussion - here is a brief rundown of them:

























Please remember that #WeCATS is a speedy critical appraisal - Here is a link to CASP's Checklists that will help and guide you.  

Please feel free to add your own Critical Appraisals or reflections on the discussion below via the comments box. 







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 #WeCATS transcript

 
@WeNurses
25 June 2015 20:00
Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@CochraneUK
25 June 2015 20:00
@RuthyB27 @CASPUK Great to have you here Ruth - hard to resist eh? #wecats
@CochraneUK
25 June 2015 20:00
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@irishinneburg
25 June 2015 20:00
Looking forward to my first journal club on Twitter #WeCATS
@KarenLynas2012
25 June 2015 20:01
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@PennyFawthrop
25 June 2015 20:01
@WeNurses I'm joining in #wave #weCATS
@CochraneUK
25 June 2015 20:01
@irishinneburg Welcome Iris! Who else is joining us? #wecats
@Mental_Elf
25 June 2015 20:01
Hello matey tweeps! It's André Tomlin here, posting elfin wisdom from the woodland this evening :-) #wecats
@CochraneUK
25 June 2015 20:01
RT @Mental_Elf: Hello matey tweeps! It's André Tomlin here, posting elfin wisdom from the woodland this evening :-) #wecats
@WeNurses
25 June 2015 20:01
Tonights #WeCATS discussion is around this paper> http://t.co/RtljTB8fyN re mindfullness for recurrent depression & will be lead by @CASPUK
@CochraneUK
25 June 2015 20:01
RT @WeNurses: Tonights #WeCATS discussion is around this paper> http://t.co/RtljTB8fyN re mindfullness for recurrent depression & will be l…
@KarenLynas2012
25 June 2015 20:01
@WeNurses @Mental_Elf love the jargon bin! #WeCATS
@CochraneConsumr
25 June 2015 20:01
RT @SarahChapman30: Read the paper ready for #WeCATS? We have! @WeNurses @Mental_Elf @CASPUK @UKCochraneCentr http://t.co/A2j7yy1n6S
@rosieneall
25 June 2015 20:01
@WeNurses #WAVE #WeCATS
@sally_crowe
25 June 2015 20:02
Hello Sally from CASP UK here #wecats
@WeDistrictNurse
25 June 2015 20:02
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@CochraneConsumr
25 June 2015 20:02
RT @WeNurses: Tonights #WeCATS discussion is around this paper> http://t.co/RtljTB8fyN re mindfullness for recurrent depression & will be l…
@lisaburscheidt
25 June 2015 20:02
What's happening? Twitter, #wecats is happening. Hullo @Mental_Elf @sally_crowe @SarahChapman30 @RuthyB27
@Mental_Elf
25 June 2015 20:02
If you notice any jargon during #WeCATS pls help me chuck it in the #JargonBin & define it so everyone can join in http://t.co/nu7pOoEjkZ
@CochraneUK
25 June 2015 20:02
RT @Mental_Elf: If you notice any jargon during #WeCATS pls help me chuck it in the #JargonBin & define it so everyone can join in http://t…
@AgencyNurse
25 June 2015 20:02
Teresa here in Bristol - a little nervous as not very good at critcal appraisal #WeCATS
@WeNursesToo
25 June 2015 20:02
RT @Mental_Elf: If you notice any jargon during #WeCATS pls help me chuck it in the #JargonBin & define it so everyone can join in http://t…
@meta4RN
25 June 2015 20:03
I'm being a #WeCATS lurker (still in bed: it's 0500 on the east coast of Australia) @UKCochraneCentr @irishinneburg
@WeNursesToo
25 June 2015 20:03
Hi Sally - over to you guys #WeCATS :D https://t.co/uC34T06tc9
@CochraneUK
25 June 2015 20:03
@AgencyNurse I think we all feel a bit worried about critical appraisal - good place to share that! #wecats
@fwilkie
25 June 2015 20:03
#WeCATS #WAVE - Fran Wilkie here, looking forward to the experiment!
@AgencyNurse
25 June 2015 20:03
RT @UKCochraneCentr: @AgencyNurse I think we all feel a bit worried about critical appraisal - good place to share that! #wecats
@WeNurses
25 June 2015 20:03
RT @UKCochraneCentr: @AgencyNurse I think we all feel a bit worried about critical appraisal - good place to share that! #wecats
@CochraneUK
25 June 2015 20:04
@meta4RN @UKCochraneCentr @irishinneburg You get a badge for effort then - thinking about critical appraisal so early!!! #wecats
@sally_crowe
25 June 2015 20:04
No need to be nervous Teresa we are just dipping out toes in the critical appraisal water! #wecats
@WeNurses
25 June 2015 20:04
Great stuff #WeCATS https://t.co/gtHefO7dtD
@CASPUK
25 June 2015 20:04
QUESTION 1: Does the research ask a clearly focused question? #WeCATS http://t.co/qmcGN546lc
@CochraneUK
25 June 2015 20:04
@fwilkie Experiment's the word! Exciting doing something new! #wecats
@AgencyNurse
25 June 2015 20:04
RT @sally_crowe: No need to be nervous Teresa we are just dipping out toes in the critical appraisal water! #wecats
@rebecca_wright2
25 June 2015 20:04
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@HealthUKTD
25 June 2015 20:04
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@CochraneUK
25 June 2015 20:04
RT @sally_crowe: No need to be nervous Teresa we are just dipping out toes in the critical appraisal water! #wecats
@PennyFawthrop
25 June 2015 20:04
@rosieneall @WeNurses Yes, I'm an undergraduate #WeCATS
@WeNursesToo
25 June 2015 20:05
What do people think ? #WeCATS https://t.co/Pcf8Ef5Uei
@meta4RN
25 June 2015 20:05
Shh! Don't wake my wife! #WeCATS :-) @UKCochraneCentr @irishinneburg
@sally_crowe
25 June 2015 20:05
By clearly focussed question we are after the who, the what and the why of the research #wecats
@CochraneUK
25 June 2015 20:05
RT @WeNursesToo: What do people think ? #WeCATS https://t.co/Pcf8Ef5Uei
@Benfelen
25 June 2015 20:05
.@UKCochraneCentr @AgencyNurse yes critical appraisal makes me nervous too! #wecats
@lisaburscheidt
25 June 2015 20:05
@meta4RN @UKCochraneCentr @irishinneburg Wow, that's dedication #wecats
@Mental_Elf
25 June 2015 20:05
RT @sally_crowe: By clearly focussed question we are after the who, the what and the why of the research #wecats
@CochraneUK
25 June 2015 20:05
@meta4RN @UKCochraneCentr @irishinneburg Undercover tweeting! #wecats
@ChenSh3
25 June 2015 20:05
RT @Mental_Elf: #WeCATS 8pm today! Free critical appraisal training http://t.co/yl9SWC6XEQ @WeNurses @CASPUK @UKCochraneCentr http://t.co/F…
@CochraneUK
25 June 2015 20:06
RT @sally_crowe: By clearly focussed question we are after the who, the what and the why of the research #wecats
@sally_crowe
25 June 2015 20:06
Who are the participants in this research? #wecats
@HealthUKTD
25 June 2015 20:06
RT @sally_crowe: No need to be nervous Teresa we are just dipping out toes in the critical appraisal water! #wecats
@CochraneUK
25 June 2015 20:06
Who's going to be brave & have a stab at saying who the participants were? #wecats
@rosieneall
25 June 2015 20:06
I put can't tell #WeCATS
@irishinneburg
25 June 2015 20:06
A1. In my opinion it does. What is effect of MBCT compared to maint antidepressant therapy 2prevent relapse/recurrence of depression #wecats
@kilgore_cliff
25 June 2015 20:06
RT @WeNurses: Tonights #WeCATS discussion is around this paper> http://t.co/RtljTB8fyN re mindfullness for recurrent depression & will be l…
@sally_crowe
25 June 2015 20:07
We could just focus on the abstract for now - a lot of what we need to know is in there... #wecats
@AgencyNurse
25 June 2015 20:07
Q1 @CASPUK well i would say it does - it clearly states background & what they intended to do #WECATS
@sharontelfer
25 June 2015 20:07
RT @WeNurses: #CriticalAppraisalTwitterSession #WeCATS #WeCATS #WeCATS #WeCATS Details > http://t.co/itKdDVOJnK Tonight 8pm http://t.…
@AmyPricePhD
25 June 2015 20:07
@CASPUK #WeCATS #1but it is not sufficient
@CochraneUK
25 June 2015 20:07
@rosieneall can't tell who the participants are you mean? #wecats
@CochraneUK
25 June 2015 20:07
@sally_crowe good plan #wecats
@sally_crowe
25 June 2015 20:07
@irishinneburg great stuff that's pretty much the core of it #wecats
@sharontelfer
25 June 2015 20:07
RT @WeNurses: The fab @Mental_Elf will be tonights #jargonbin monitor (please feel free to chuck all jargon in the bin) #WeCATS http://t.co…
@massagetherapy
25 June 2015 20:07
RT @WeNurses: Tonights #WeCATS discussion is around this paper> http://t.co/RtljTB8fyN re mindfullness for recurrent depression & will be l…
@WeNurses
25 June 2015 20:07
Quiet as cats here ... errrr mice we mean #WeCATS https://t.co/lF1IP2iO94
@CASPUK
25 June 2015 20:08
Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/ElpGIJmSCm
@massagetherapy
25 June 2015 20:08
RT @UKCochraneCentr: @AgencyNurse I think we all feel a bit worried about critical appraisal - good place to share that! #wecats
@CochraneUK
25 June 2015 20:08
We get something about participants in the 1st line of the background, in the abstract #wecats
@WeNursesToo
25 June 2015 20:08
Great tip thank you #WeCATS https://t.co/4i99UtdXUH
@HealthUKTD
25 June 2015 20:08
RT @sally_crowe: By clearly focussed question we are after the who, the what and the why of the research #wecats
@irishinneburg
25 June 2015 20:08
A1. Patients with recurrent major depressive disorder in full or partial remission, at least 3 prior major depression episodes #wecats
@CochraneUK
25 June 2015 20:08
ooh - see I did a silly thin there... #wecats
@jonnysoapbox
25 June 2015 20:09
My kittens are weary and sleeping and I am at #WeCATS I'm a @CASPUK facilitator in South Wales Hello everyone
@Benfelen
25 June 2015 20:09
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@AgencyNurse
25 June 2015 20:09
@sally_crowe errrmmm ammending my answer a little then ... definitely why and what .. going back to check who ... #WeCATS
@CochraneUK
25 June 2015 20:09
@irishinneburg Got it! #wecats
@AmyPricePhD
25 June 2015 20:09
@CASPUK #WeCats # 1 in addition 2 focused ? clear outcomes R needed and appropriate population
@sally_crowe
25 June 2015 20:09
What do we think about the intervention? How well is it described? #wecats
@CochraneUK
25 June 2015 20:09
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@sally_crowe
25 June 2015 20:09
@jonnysoapbox @CASPUK hello Jon thanks for joining us! #wecats
@hammerslibrary
25 June 2015 20:10
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@PennyFawthrop
25 June 2015 20:10
@CASPUK I think it clearly states what the study is about #WeCATS
@sally_crowe
25 June 2015 20:11
MBCT is the intervention peeps we think that the TS means tapering support i.e coming off the anti Ds #wecats
@MumStock
25 June 2015 20:11
RT @WeNurses: The fab @Mental_Elf will be tonights #jargonbin monitor (please feel free to chuck all jargon in the bin) #WeCATS http://t.co…
@CochraneUK
25 June 2015 20:11
@sally_crowe it's one of the things that can trip us up, isn't it? Keep having to check back for acronym meaning #wecats
@B_thatguy
25 June 2015 20:11
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@AinnaFawHen
25 June 2015 20:11
RT @WeNurses: The fab @Mental_Elf will be tonights #jargonbin monitor (please feel free to chuck all jargon in the bin) #WeCATS http://t.co…
@sally_crowe
25 June 2015 20:12
@UKCochraneCentr @sally_crowe indeed it is! #wecats
@gmckee89
25 June 2015 20:12
how does this go? #WeCATS
@SandallJane
25 June 2015 20:12
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@AgencyNurse
25 June 2015 20:12
says where they were from & "diagnosis of recurrent major depressive disorder in full or partial remission" #WeCATS https://t.co/auoEkLuegm
@AgencyNurse
25 June 2015 20:12
RT @sally_crowe: We could just focus on the abstract for now - a lot of what we need to know is in there... #wecats
@WeNursesToo
25 June 2015 20:12
RT @sally_crowe: We could just focus on the abstract for now - a lot of what we need to know is in there... #wecats
@UCLanODP
25 June 2015 20:12
#WeCATS so does mcbt reduce antidepressant use ?
@EmmaBettyHughes
25 June 2015 20:12
I think it clearly states the intervention and which group was going to get which treatment #weCATS
@AgencyNurse
25 June 2015 20:12
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@WeNurses
25 June 2015 20:12
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@sally_crowe
25 June 2015 20:13
So if the intervention was MBCT (mindfulness training) what was this being compared to? The control #wecats
@sally_crowe
25 June 2015 20:13
@EmmaBettyHughes that's good #wecats
@gmckee89
25 June 2015 20:13
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@CochraneUK
25 June 2015 20:13
@EmmaBettyHughes I think we get a pretty good description of the intervention #wecats
@meta4RN
25 June 2015 20:13
Do acronyms belong in the #JargonBin or is that being too harsh? #WeCATS @UKCochraneCentr @sally_crowe
@AmyPricePhD
25 June 2015 20:13
@lisaburscheidt @CASPUK #WeCATS no quality of life or interview with pts, Already on drugs with 3 episodes low recovery stats
@WeNursesToo
25 June 2015 20:13
hello there #WeCATS https://t.co/fsuqIh27oN
@gmckee89
25 June 2015 20:13
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@sally_crowe
25 June 2015 20:13
@AgencyNurse this is an important piece of description thanks #wecats
@CochraneUK
25 June 2015 20:13
RT @sally_crowe: So if the intervention was MBCT (mindfulness training) what was this being compared to? The control #wecats
@rosemariecurry
25 June 2015 20:13
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@Mental_Elf
25 June 2015 20:13
@meta4RN @UKCochraneCentr @sally_crowe YES! Especially acronyms #wecats
@POL_Research
25 June 2015 20:14
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@irishinneburg
25 June 2015 20:14
A1. Interventions (MBCT and control) are described in detail in section "Procedures" #wecats
@WeNursesToo
25 June 2015 20:14
Good question #WeCATS https://t.co/8jdmTfMAOb
@lisaburscheidt
25 June 2015 20:14
@gmckee89 Hi Geraldine! We just discussed the first question - if you click the hashtag #wecats you can join us for the second.
@CochraneUK
25 June 2015 20:14
@meta4RN @UKCochraneCentr @sally_crowe I'd say it's ok if authors clearly say what they are on first use. #wecats
@WeNursesToo
25 June 2015 20:14
RT @PennyFawthrop: @CASPUK I think it clearly states what the study is about #WeCATS
@HealthUKTD
25 June 2015 20:14
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@sally_crowe
25 June 2015 20:14
@irishinneburg thanks great - not a conventional usual care but maintenance anti Ds #wecats
@CochraneUK
25 June 2015 20:14
RT @irishinneburg: A1. Interventions (MBCT and control) are described in detail in section "Procedures" #wecats
@AgencyNurse
25 June 2015 20:14
TS ?? #JargonBin #WeCATS https://t.co/Caph4SpyXw
@CochraneUK
25 June 2015 20:15
RT @sally_crowe: @irishinneburg thanks great - not a conventional usual care but maintenance anti Ds #wecats
@Mental_Elf
25 June 2015 20:15
@sally_crowe @irishinneburg The other option would have been an attention control group #wecats
@sally_crowe
25 June 2015 20:15
@AgencyNurse yes we can put that in the jargon bin! #wecats
@CochraneUK
25 June 2015 20:15
RT @Mental_Elf: @sally_crowe @irishinneburg The other option would have been an attention control group #wecats
@POL_Research
25 June 2015 20:15
RT @UKCochraneCentr: @fwilkie Experiment's the word! Exciting doing something new! #wecats
@AgencyNurse
25 June 2015 20:15
#phew #wecats https://t.co/KY39y4QcMz
@Mental_Elf
25 June 2015 20:15
@AgencyNurse TS = Tapering Support (i.e. coming off their antidepressants) #wecats
@CochraneUK
25 June 2015 20:15
@Mental_Elf @sally_crowe @irishinneburg #JARGONBIN - or does everyone know what an attention control group is? #wecats
@AgencyNurse
25 June 2015 20:16
Thank you #WeCATS https://t.co/RQVBOu5HxJ
@WeNursesToo
25 June 2015 20:16
RT @Mental_Elf: @AgencyNurse TS = Tapering Support (i.e. coming off their antidepressants) #wecats
@HoylandH
25 June 2015 20:16
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@AgencyNurse
25 June 2015 20:16
nope #WeCATS #JargonBin https://t.co/SnKElbZJql
@POL_Research
25 June 2015 20:16
RT @WeNurses: #CriticalAppraisalTwitterSession #WeCATS #WeCATS #WeCATS #WeCATS Details > http://t.co/itKdDVOJnK Tonight 8pm http://t.…
@petedenton
25 June 2015 20:17
RT @Mental_Elf: I'm jargon monitor at #WeCATS, but please help me out. If you notice any tricky language, stick it in the #JargonBin http:/…
@Mental_Elf
25 June 2015 20:17
This paper gives you more detail on attention control groups: http://t.co/2rztRAfqsS #wecats
@AgencyNurse
25 June 2015 20:17
RT @Mental_Elf: This paper gives you more detail on attention control groups: http://t.co/2rztRAfqsS #wecats
@WeNursesToo
25 June 2015 20:17
RT @Mental_Elf: This paper gives you more detail on attention control groups: http://t.co/2rztRAfqsS #wecats
@sally_crowe
25 June 2015 20:17
ok why don't we move on to the outcomes what were they measuring in this study to see if mindfulness was effective? #wecats
@CochraneUK
25 June 2015 20:18
@Mental_Elf please tell us what you mean by an attention control group #WeCATS https://t.co/8h5F8qj1L4
@ALLIANCE_INet
25 June 2015 20:18
RT @Mental_Elf: If you notice any jargon during #WeCATS pls help me chuck it in the #JargonBin & define it so everyone can join in http://t…
@sally_crowe
25 June 2015 20:18
So far we have talked about P population I intervention and C control now lets think about the outcomes? #wecats
@WeNursesToo
25 June 2015 20:18
What do people think ? #WeCATS https://t.co/RoBlpOug1k
@lisaburscheidt
25 June 2015 20:18
@AmyPricePhD make sure you hashtag with #wecats otherwise it won't show up in main discussion
@CASPUK
25 June 2015 20:18
Here's an example #PICO question for patients with acute asthma #WeCATS http://t.co/slOudw783Y
@CochraneUK
25 June 2015 20:18
RT @Mental_Elf: This paper gives you more detail on attention control groups: http://t.co/2rztRAfqsS #wecats
@jonathan_davis3
25 June 2015 20:18
RT @CASPUK: Here's an example #PICO question for patients with acute asthma #WeCATS http://t.co/slOudw783Y
@CochraneUK
25 June 2015 20:19
@Mental_Elf really helpful to have links we can all check later #WeHomework! #wecats
@CochraneUK
25 June 2015 20:19
RT @CASPUK: Here's an example #PICO question for patients with acute asthma #WeCATS http://t.co/slOudw783Y
@CochraneUK
25 June 2015 20:19
RT @lisaburscheidt: @AmyPricePhD make sure you hashtag with #wecats otherwise it won't show up in main discussion
@sally_crowe
25 June 2015 20:19
Primary (main) outcome was recurrence of depression #wecats
@CASPUK
25 June 2015 20:19
QUESTION 2: Is the research study design appropriate for the question? Will the results inform the Q? #WeCATS http://t.co/flirVgDLsa
@fwilkie
25 June 2015 20:20
@sally_crowe #WeCATS outcome= time to relapse or recurrence of depression
@EmmaBettyHughes
25 June 2015 20:20
@sally_crowe yes, to see if it was more effective than anti-depress meds in preventing relapse. accounting for costs etc too #weCATS
@CochraneUK
25 June 2015 20:20
@sally_crowe Thanks for clarifying primary - so many words can be tripwires for the person learning to critically appraise #wecats
@HealthUKTD
25 June 2015 20:20
RT @Mental_Elf: This paper gives you more detail on attention control groups: http://t.co/2rztRAfqsS #wecats
@sally_crowe
25 June 2015 20:20
Now we are going to focus on the way the study was designed #wecats
@irishinneburg
25 June 2015 20:20
primary outcome was time to relapse or recurrence of depression #wecats
@PhsmSam
25 June 2015 20:20
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@sally_crowe
25 June 2015 20:21
@EmmaBettyHughes @sally_crowe great to see costs in here really helps in decision making #wecats
@CochraneUK
25 June 2015 20:21
@irishinneburg great yes - this is clearly laid out I think. Good! #wecats
@CochraneUK
25 June 2015 20:21
RT @sally_crowe: @EmmaBettyHughes @sally_crowe great to see costs in here really helps in decision making #wecats
@CochraneUK
25 June 2015 20:21
@sally_crowe @EmmaBettyHughes all too unusual too #wecats
@sally_crowe
25 June 2015 20:21
What do we think about randomized trials? Are they a good way to fairly test a treatment? #wecats
@CochraneUK
25 June 2015 20:21
RT @CASPUK: QUESTION 2: Is the research study design appropriate for the question? Will the results inform the Q? #WeCATS http://t.co/flirV…
@WeNursesToo
25 June 2015 20:21
RT @sally_crowe: Primary (main) outcome was recurrence of depression #wecats
@AgencyNurse
25 June 2015 20:21
RT @sally_crowe: Primary (main) outcome was recurrence of depression #wecats
@NicolaTrevor1
25 June 2015 20:22
The design seems appropriate to inform question. #WeCATS
@CochraneUK
25 June 2015 20:22
@CASPUK what do people think? #wecats
@irishinneburg
25 June 2015 20:22
A2. Randomization process seems fine to me - described as computer-generated #wecats
@sally_crowe
25 June 2015 20:22
@NicolaTrevor1 thanks Nicola #wecats
@WeNursesToo
25 June 2015 20:22
Q2 #WECATS https://t.co/gi2AE3hRND
@AgencyNurse
25 June 2015 20:22
RT @fwilkie: @sally_crowe #WeCATS outcome= time to relapse or recurrence of depression
@CochraneUK
25 June 2015 20:22
@irishinneburg agree - we get more detail about randomization than is often the case #wecats
@WeNursesToo
25 June 2015 20:22
#WeCATS https://t.co/nF1JGXhIFB
@sally_crowe
25 June 2015 20:22
Who was 'blinded' in the trial? Does this matter? #wecats
@wlasinclair
25 June 2015 20:23
RT @CASPUK: QUESTION 2: Is the research study design appropriate for the question? Will the results inform the Q? #WeCATS http://t.co/flirV…
@WeNursesToo
25 June 2015 20:23
RT @NicolaTrevor1: The design seems appropriate to inform question. #WeCATS
@CochraneUK
25 June 2015 20:23
RT @sally_crowe: Who was 'blinded' in the trial? Does this matter? #wecats
@LasLynda
25 June 2015 20:23
RT @WeNurses: Helloooo and welcome to the first #WeCATS discussion Please give us a #WAVE if you are joining us http://t.co/FOX11fcUAM
@lisaburscheidt
25 June 2015 20:23
@sally_crowe yes if done well and with an appropriate control, as mentioned earlier #wecats
@CochraneUK
25 June 2015 20:23
@sally_crowe blinding #JARGONBIN potential. Single blinded - do you all know what that is? #wecats
@irishinneburg
25 June 2015 20:23
.@sally_crowe Randomization makes sure that both groups are comparable at the start of the trial #wecats
@AgencyNurse
25 June 2015 20:23
I would say yes but have to be properly conducted .. large enough amount of subjects etc #WeCATS https://t.co/WluBdNt6sc
@IMLahart
25 June 2015 20:23
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@NicolaTrevor1
25 June 2015 20:24
Does anyone think there is anything in the trial design that would mean a difference would be missed? #WeCATS
@UCLanODP
25 June 2015 20:24
@sally_crowe #wecats rct is what we are led to think is reasonable method
@uniquespaday
25 June 2015 20:24
Hi sorry new to Twitter how do you join #WeCATS
@irishinneburg
25 June 2015 20:24
.@sally_crowe Patients not blinded (hard to achieve in this setting), but researchers who judge outcomes #wecats
@Mental_Elf
25 June 2015 20:24
Blinding = Actions intended to prevent study participants or the researchers from knowing which participant received which treatment #wecats
@sally_crowe
25 June 2015 20:25
@uclanodp @UKCochraneCentr much better if authors describe who was blinded and why? Rather than single, double triple blinded! #wecats
@CochraneUK
25 June 2015 20:25
I see they talk about 'masking' - all ok with that? Section on blinding or masking on p.2 #wecats
@Jo__Howe
25 June 2015 20:25
Not sure if the patients were equally matched in terms of demographics or medical criteria #wecats
@AgencyNurse
25 June 2015 20:25
Q2 @CASPUK i think the only thing that worrys me is the mindfulness therapy itself #WeCATS As it was delivered by two therapists
@PowysFalls
25 June 2015 20:25
RT @WeNurses: Dont forget that tonights #WeNurses hashtag is #WeCATS :D
@sally_crowe
25 June 2015 20:25
@Jo__Howe interesting Jo in what way? #wecats
@lisaburscheidt
25 June 2015 20:25
Throwing "blinding" into the #jargonbin, so many ppl come to my sessions being really confused about what it is and why it's done #wecats
@CochraneUK
25 June 2015 20:25
RT @Jo__Howe: Not sure if the patients were equally matched in terms of demographics or medical criteria #wecats
@sally_crowe
25 June 2015 20:25
masking is another word used for blinding folks #wecats
@lisaburscheidt
25 June 2015 20:26
He's beat me to it already, speedy Elf #wecats https://t.co/F3Rp14DfAn
@jonnysoapbox
25 June 2015 20:26
If the patients know what part of the trial they are in does that matter? #WeCATS
@Jo__Howe
25 June 2015 20:26
Usually in research with RCTs we would match through randomisation to age, gender, time of onset to ensure both groups equal #wecats
@AgencyNurse
25 June 2015 20:26
@CASPUK am i right in saying no mention of content consistency of minfulness therapy ? or have i misread ? #WeCATS
@CochraneUK
25 June 2015 20:26
RT @sally_crowe: masking is another word used for blinding folks #wecats
@RuthyB27
25 June 2015 20:26
@uniquespaday Hi, follow the hashtag #weCATS & look out for @sally_crowe @CASPUK tweet questions
@Mental_Elf
25 June 2015 20:26
"The fidelity of this masking was moderate" - they could've said that clearer guvnor! #JargonBin #wecats
@sally_crowe
25 June 2015 20:26
so to summarise in this study just the data analysts were blind to whose data they were analysing - treatment or control #wecats
@AgencyNurse
25 June 2015 20:26
RT @irishinneburg: A2. Randomization process seems fine to me - described as computer-generated #wecats
@WeNurses
25 June 2015 20:26
RT @irishinneburg: A2. Randomization process seems fine to me - described as computer-generated #wecats
@CochraneUK
25 June 2015 20:26
@sally_crowe @uclanodp @UKCochraneCentr yes much better! #wecats
@CASPUK
25 June 2015 20:26
Here is the basic design of a Randomised Controlled Trial #RCT #WeCATS http://t.co/lF91ktbqpm
@Jo__Howe
25 June 2015 20:27
Another thing they could have done is video taped all the sessions and marked the assessors and or therapsitst from the videos #wecats
@VerityTay
25 June 2015 20:27
RT @AgencyNurse: Q2 @CASPUK i think the only thing that worrys me is the mindfulness therapy itself #WeCATS As it was delivered by two th…
@AgencyNurse
25 June 2015 20:27
#jargonbin "blinded" #wecats https://t.co/xIXbXzEh2J
@jonnysoapbox
25 June 2015 20:27
Did the clinicians know, and does that matter? #WeCATS
@UCLanODP
25 June 2015 20:27
@UKCochraneCentr #wecats interesting blinding /masking ? Difference
@sally_crowe
25 June 2015 20:27
They did quite a bit of quality control of the therapists - a sign of a good trial #wecats
@Jo__Howe
25 June 2015 20:27
@WeNurses @irishinneburg that could be excel though - #wecats
@AmyPricePhD
25 June 2015 20:28
@EmmaBettyHughes @sally_crowe Unclear how costs assessed & worry telling all patients 2 take meds would bias withdrawal #WeCats
@CochraneUK
25 June 2015 20:28
Only research assessors were 'blinded/masked' to which treatment group each person was in #wecats
@NicolaTrevor1
25 June 2015 20:28
@jonnysoapbox knowing your treatment can influence how you feel and whether you think the treatment is working #WeCATS
@AgencyNurse
25 June 2015 20:28
Yes i think the therapy sessions should have been structured the same .. they may have been but doesnt say #WeCATS https://t.co/LrezXf3TAb
@irishinneburg
25 June 2015 20:28
.@Jo__Howe and to all the other factors we might not even know that they are influencing the outcome (= confounders) #wecats
@AinnaFawHen
25 June 2015 20:28
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@CochraneUK
25 June 2015 20:28
@jonnysoapbox yes they did and that's a good question. What do people think? Did it matter that clinicians knew which treatment? #wecats
@HealthUKTD
25 June 2015 20:28
RT @irishinneburg: A2. Randomization process seems fine to me - described as computer-generated #wecats
@CoxonGeorge
25 June 2015 20:28
RT @WeKittens: Don't forget #WeCATS chat tonight at 8pm! Mindfulness For Recurrent Depression (@TheLancet #RCT) http://t.co/tvB7u2UA4o
@CochraneUK
25 June 2015 20:28
RT @AgencyNurse: Yes i think the therapy sessions should have been structured the same .. they may have been but doesnt say #WeCATS https:…
@CochraneUK
25 June 2015 20:29
@AgencyNurse good point #wecats
@UCLanODP
25 June 2015 20:29
@uniquespaday you're here Paul prefix responses with #wecats
@PennyFawthrop
25 June 2015 20:29
@jonnysoapbox to be honest I don't know as I read it online, no page numbers! Also, I am new to all this #WeCATS
@AgencyNurse
25 June 2015 20:29
@Mental_Elf surely in the case the particpants would have known which treatment they recieved ? #wecats
@sally_crowe
25 June 2015 20:29
A trial design helps to address the other issues (apart from the intervention) that might affect the outcomes #wecats
@AmyPricePhD
25 June 2015 20:29
#WeCATS mixed methods would B more informative RCT + qualitative research https://t.co/1mX051hBaZ
@CochraneUK
25 June 2015 20:30
@PennyFawthrop @jonnysoapbox That's something for us to be aware of - not all will see page numbers! Thanks #wecats
@Emma_Leigh_MBE
25 June 2015 20:30
RT @Mental_Elf: If you notice any jargon during #WeCATS pls help me chuck it in the #JargonBin & define it so everyone can join in http://t…
@Mental_Elf
25 June 2015 20:30
@AgencyNurse @Mental_Elf Yes they did - can't have it any other way in this trial #wecats
@AgencyNurse
25 June 2015 20:30
ok - so could this have affected the research then ? #wecats https://t.co/uh0lFIdc2x
@CochraneUK
25 June 2015 20:30
RT @sally_crowe: A trial design helps to address the other issues (apart from the intervention) that might affect the outcomes #wecats
@Jo__Howe
25 June 2015 20:30
Does it mention whether the assessors blindedness was checked? Usually would ask if they knew which treatment patient had #wecats
@CASPUK
25 June 2015 20:30
QUESTION 3: Are the participants in the study all accounted for? Did any drop out and do we know why? #WeCATS http://t.co/ZL2B83sFnw
@sally_crowe
25 June 2015 20:30
@AmyPricePhD agree Amy! #wecats
@RuthyB27
25 June 2015 20:30
RT @sally_crowe: A trial design helps to address the other issues (apart from the intervention) that might affect the outcomes #wecats
@AgencyNurse
25 June 2015 20:31
@Mental_Elf so there was no blindness ... but yes surely no choice. #WeCATS Does this affect the accuracy ?
@NicolaTrevor1
25 June 2015 20:31
@AmyPricePhD How would mixed methods be better? #WeCATS
@CochraneUK
25 June 2015 20:31
@Jo__Howe yes we get info on how many people assessors correctly guessed treatment allocation #wecats
@sally_crowe
25 June 2015 20:31
The diagram of people running away from the trial is to illustrate that in real life ppl do leave studies for lots of reasons #wecats
@CochraneUK
25 June 2015 20:31
@AgencyNurse @Mental_Elf research assessors were blind to treatment allocation #wecats
@rosieneall
25 June 2015 20:31
RT @caspuk: QUESTION 3: Are the participants in the study all accounted for? Did any drop out and do we know why? #WeCATS
@Mental_Elf
25 June 2015 20:31
@Jo__Howe It does "The fidelity of this masking was moderate with assessors correctly guessing allocation for 56% of assessments" #wecats
@WeNurses
25 June 2015 20:32
Indeed !!!!! #eek #WeCATS https://t.co/cjlKXZMyQO
@AgencyNurse
25 June 2015 20:32
RT @UKCochraneCentr: @AgencyNurse @Mental_Elf research assessors were blind to treatment allocation #wecats
@WeNursesToo
25 June 2015 20:32
RT @CASPUK: Here is the basic design of a Randomised Controlled Trial #RCT #WeCATS http://t.co/lF91ktbqpm
@AgencyNurse
25 June 2015 20:32
RT @CASPUK: Here is the basic design of a Randomised Controlled Trial #RCT #WeCATS http://t.co/lF91ktbqpm
@sally_crowe
25 June 2015 20:32
@NicolaTrevor1 @AmyPricePhD as well as assessing effectiveness we may find out more about mindfulness? #wecats
@AmyPricePhD
25 June 2015 20:32
@EmmaBettyHughes @sally_crowe cost £112 per participant is this platform start up etc or just standard therapy #WeCats
@irishinneburg
25 June 2015 20:32
A3. The patient 'flow' in the trial is given in Figure 1 #wecats
@CASPUK
25 June 2015 20:32
Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@AgencyNurse
25 June 2015 20:32
ahhh yes would have felt happier about this #WeCATS https://t.co/nzoAyafFcT
@PhyllBuc
25 June 2015 20:32
Now 4 1st time MT“@sally_crowe: @CASPUK tweetchat #WeCATS on 25th June 8-9pm see you there! http://t.co/12yMJFiDPB” https://t.co/iiFu4HGz5R
@CochraneUK
25 June 2015 20:32
RT @CASPUK: Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@United4Evidence
25 June 2015 20:32
RT @sally_crowe: A trial design helps to address the other issues (apart from the intervention) that might affect the outcomes #wecats
@UCLanODP
25 June 2015 20:33
@sally_crowe #wecats as is their right to
@rosieneall
25 June 2015 20:33
#WeCATS figure 1 on page 4 shows the number of participants lost to follow-up or withdrew from the study
@WeNurses
25 June 2015 20:33
RT @CASPUK: QUESTION 3: Are the participants in the study all accounted for? Did any drop out and do we know why? #WeCATS http://t.co/ZL2B8…
@AgencyNurse
25 June 2015 20:33
RT @CASPUK: QUESTION 3: Are the participants in the study all accounted for? Did any drop out and do we know why? #WeCATS http://t.co/ZL2B8…
@sally_crowe
25 June 2015 20:33
Look for a nice diagram that shows who started and who finished! Called a flow diagram and it is on page 4 of the paper #wecats
@LasLynda
25 June 2015 20:33
RT @rosieneall: Any undergraduate or postgraduate student's joining tonight's #WeCATS tweet?
@PennyFawthrop
25 June 2015 20:33
#WeCATS I'm learning that research papers need to be read several times for appraisals to be made. Going off first impressions #newtoallthis
@CochraneUK
25 June 2015 20:33
@irishinneburg I think this is a useful way to show it - we can see the participants & what happened at each stage #wecats
@Jo__Howe
25 June 2015 20:33
RT @PennyFawthrop: #WeCATS I'm learning that research papers need to be read several times for appraisals to be made. Going off first impre…
@CochraneUK
25 June 2015 20:34
RT @PennyFawthrop: #WeCATS I'm learning that research papers need to be read several times for appraisals to be made. Going off first impre…
@CochraneUK
25 June 2015 20:34
@PennyFawthrop you're right there! They can be so hard to pick apart #wecats
@AmyPricePhD
25 June 2015 20:34
#WeCats could assess quality of life, individual experience, motivation 4 returning or discontinuing meds, 1/2 https://t.co/Mmj79MHuOV
@CASPUK
25 June 2015 20:34
Here's figure 1 from the paper #WeCATS You can see what happened to trial participants at each stage http://t.co/EMcMO6z3aC
@Jo__Howe
25 June 2015 20:34
@UKCochraneCentr @PennyFawthrop it does get easier to "get the jist" with practice #wecats
@CochraneUK
25 June 2015 20:34
@sally_crowe This is good isn't it? #wecats
@sally_crowe
25 June 2015 20:34
Anyone else think that they have exactly the same figures in the trial flow diagram between the intervention and the control groups? #wecats
@lisaburscheidt
25 June 2015 20:35
@rosieneall Indeed, thanks Rosie! #wecats
@AgencyNurse
25 June 2015 20:35
Q3 @CASPUK Its clear that some participants dropped out but a large percentage stayed .. very good table explaining this #WeCATS
@AmyPricePhD
25 June 2015 20:35
#WeCats 2/2 could C participants happy with trial how 2 improve, what other meds/life happened during trial https://t.co/Mmj79MHuOV
@sally_crowe
25 June 2015 20:35
So sadly 2 people died in each arm of the trial, and 17 were lost to follow up or withdrew in each arm - comments? #wecats
@WeNursesToo
25 June 2015 20:35
RT @CASPUK: Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@AgencyNurse
25 June 2015 20:35
RT @CASPUK: Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@Jo__Howe
25 June 2015 20:36
@sally_crowe strange co-incidence perhaps? #wecats
@CochraneUK
25 June 2015 20:36
Q3 Are people happy with what 'intention-to-treat' means? #wecats
@AgencyNurse
25 June 2015 20:36
I did #smugface #WeCATS https://t.co/8xszKb7jSA
@CASPUK
25 June 2015 20:36
Here's how the @NICEcomms glossary defines 'Intention to Treat' #WeCATS (not Intention to Tweet!) http://t.co/mtnZfxOXDo
@sally_crowe
25 June 2015 20:36
@AgencyNurse @CASPUK yes the 'stickability' of this trial was good #wecats
@HealthUKTD
25 June 2015 20:36
RT @CASPUK: QUESTION 3: Are the participants in the study all accounted for? Did any drop out and do we know why? #WeCATS http://t.co/ZL2B8…
@CochraneUK
25 June 2015 20:36
@sally_crowe @AgencyNurse @CASPUK That's a good term! #wecats
@CochraneUK
25 June 2015 20:37
RT @CASPUK: Here's how the @NICEcomms glossary defines 'Intention to Treat' #WeCATS (not Intention to Tweet!) http://t.co/mtnZfxOXDo
@CASPUK
25 June 2015 20:37
QUESTION 4: What are main results of the research? Are they significant statistically or clinically or both? #WeCATS http://t.co/EOGQcN7t3D
@AgencyNurse
25 June 2015 20:37
Me too Penny - keep going .. i'm asking lots of daft questions #learning #wecats https://t.co/xQEV6Tle0d
@WeNursesToo
25 June 2015 20:37
RT @sally_crowe: @AgencyNurse @CASPUK yes the 'stickability' of this trial was good #wecats
@sally_crowe
25 June 2015 20:37
hold on to your hats then its results time! #wecats
@NicolaTrevor1
25 June 2015 20:37
Sounds like this would be much more informative for clinical practice #WeCATS https://t.co/ZhhV9LeUzj
@WeNursesToo
25 June 2015 20:37
RT @CASPUK: Here's figure 1 from the paper #WeCATS You can see what happened to trial participants at each stage http://t.co/EMcMO6z3aC
@AmyPricePhD
25 June 2015 20:37
@NicolaTrevor1 #WeCATS could C if participants had tech glitches & when & Y they disengaged
@CochraneUK
25 June 2015 20:37
@CASPUK @NICEcomms very simply, intention to treat ignores anything that happens after randomisation! #wecats
@sally_crowe
25 June 2015 20:37
no question is a daft question in wecats! #wecats
@SteriuMD
25 June 2015 20:37
RT @CASPUK: Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@Mental_Elf
25 June 2015 20:38
@sally_crowe Ooh - that's a challenge! #wecats
@lisaburscheidt
25 June 2015 20:38
@sally_crowe either a weird cooincodence or bad copy&paste as nobody proofreads diagrams? ppl dying = very sad in any case. #wecats
@WeNursesToo
25 June 2015 20:38
any thoughts here #WeCATS https://t.co/MWyH4N6cbo
@United4Evidence
25 June 2015 20:38
ITT: "once randomized, always analyzed" @UKCochraneCentr @CASPUK #wecats
@HealthUKTD
25 June 2015 20:38
RT @CASPUK: Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@htona_rus
25 June 2015 20:38
RT @CASPUK: Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@CochraneUK
25 June 2015 20:38
RT @United4Evidence: ITT: "once randomized, always analyzed" @UKCochraneCentr @CASPUK #wecats
@CochraneUK
25 June 2015 20:39
@United4Evidence @UKCochraneCentr @CASPUK That's neat! #wecats
@rosieneall
25 June 2015 20:39
@sally_crowe I am always cautious of studies reporting the same numbers for both arms #WeCATS
@AgencyNurse
25 June 2015 20:39
could i please chuck that in the #jargonbin too #WeCATS https://t.co/eW5ZSg60Y9
@AmyPricePhD
25 June 2015 20:39
@sally_crowe @NicolaTrevor1 Yes, that would B important $ future could intervention B tailored better R other qualities important #WeCats
@sally_crowe
25 June 2015 20:39
any offers of a result for this trial in words or numbers? #wecats
@NatalieBlencowe
25 June 2015 20:39
RT @United4Evidence: ITT: "once randomized, always analyzed" @UKCochraneCentr @CASPUK #wecats
@lisaburscheidt
25 June 2015 20:39
@sally_crowe dun dun dun #wecats
@AmyPricePhD
25 June 2015 20:39
RT @NicolaTrevor1: Sounds like this would be much more informative for clinical practice #WeCATS https://t.co/ZhhV9LeUzj
@AgencyNurse
25 June 2015 20:39
i guess that naturally some people will be lost - it seems minimal to me - sad about the deaths though #wecats https://t.co/W9cUehtNeN
@irishinneburg
25 June 2015 20:40
A5. No statist. significant difference in primary outcome (time to relapse or recurrence), not in relapse rate either #wecats
@CASPUK
25 June 2015 20:40
We suggest you look in the abstract for this information. The abstract should describe the results simply #WeCATS http://t.co/7qpXhUzyU0
@CASPUK
25 June 2015 20:40
RT @United4Evidence: ITT: "once randomized, always analyzed" @UKCochraneCentr @CASPUK #wecats
@United4Evidence
25 June 2015 20:40
ITT also keeps randomization intact! MT @CASPUK @NICEcomms very simply, [ITT] ignores anything that happens after randomisation! #wecats
@CochraneUK
25 June 2015 20:40
@AgencyNurse it's in the bin! #wecats
@PennyFawthrop
25 June 2015 20:40
@AgencyNurse lifelong learning is important for all of us. Lovely to meet you yesterday. #WeCATS
@AmyPricePhD
25 June 2015 20:40
RT @United4Evidence: ITT: "once randomized, always analyzed" @UKCochraneCentr @CASPUK #wecats
@NicolaTrevor1
25 June 2015 20:40
No detected difference #WeCATS
@UCLanODP
25 June 2015 20:40
@Jo__Howe @sally_crowe #wecats can't see we reasons for deaths explained unsure about coincidence ?
@JohnBaker_Leeds
25 June 2015 20:41
Loving all this critique #wecats
@sally_crowe
25 June 2015 20:41
In a nutshell this trial did not have a statistically significant result - used something called a hazard ratio #wecats
@CochraneUK
25 June 2015 20:41
RT @sally_crowe: In a nutshell this trial did not have a statistically significant result - used something called a hazard ratio #wecats
@Jo__Howe
25 June 2015 20:41
@uclanodp @sally_crowe Not always easy to get the information surrounding death if you don't have direct access medical records #wecats
@WeNursesToo
25 June 2015 20:41
Treat not Tweet .. a clear distinction ;D #WeCATS https://t.co/HYNPR4diw6
@htona_rus
25 June 2015 20:41
RT @CASPUK: Here's an example #PICO question for patients with acute asthma #WeCATS http://t.co/slOudw783Y
@PennyFawthrop
25 June 2015 20:42
@Mental_Elf @AgencyNurse Thanks Teresa, I have no idea what that statement means #WeCATS
@AmyPricePhD
25 June 2015 20:42
#WeCats B good to know #s in population without meds or mindfulness for death and treatment dropout https://t.co/lCSIRhZzpZ
@htona_rus
25 June 2015 20:42
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@RuthyB27
25 June 2015 20:42
RT @sally_crowe: In a nutshell this trial did not have a statistically significant result - used something called a hazard ratio #wecats
@AgencyNurse
25 June 2015 20:42
and lovely to meet you :D #wecats https://t.co/HHWb5vcyfV
@CochraneUK
25 June 2015 20:42
@sally_crowe I did think about how I'd tackle hazard ratios is a tweet but gave up! Hope someone can link to something! #wecats
@sally_crowe
25 June 2015 20:42
I guess we don't need to know how to calculate a hazard ratio or even understand it but we do need to know how to interpret it #wecats
@mary_titchener
25 June 2015 20:42
RT @Mental_Elf: If you notice any jargon during #WeCATS pls help me chuck it in the #JargonBin & define it so everyone can join in http://t…
@CASPUK
25 June 2015 20:42
Deaths in trial participants were said to be not related to the trial itself #WeCATS http://t.co/qqaHXCVvDV
@CochraneUK
25 June 2015 20:42
@Mental_Elf hazard ratio? #JARGONBIN #wecats
@WeKittens
25 June 2015 20:42
#WeCATS https://t.co/hmEDagjrqo
@CochraneUK
25 June 2015 20:42
@sally_crowe yes exactly #wecats
@jonnysoapbox
25 June 2015 20:42
#WeCATS says not due to either treatment? https://t.co/kZtRxucXRX
@WeNurses
25 June 2015 20:43
you heard the lady ..... please feel free to ask any questions #WeCATS https://t.co/zrgWopuOW0
@CASPUK
25 June 2015 20:43
Confidence Intervals give us the range within which the true size of effect (never exactly known) lies #WeCATS http://t.co/FgOTbiMdTK
@irishinneburg
25 June 2015 20:43
.@sally_crowe Hazard ratio is a measure to compare time-to-event for two groups #wecats
@CochraneUK
25 June 2015 20:43
RT @CASPUK: Confidence Intervals give us the range within which the true size of effect (never exactly known) lies #WeCATS http://t.co/FgOT…
@Jo__Howe
25 June 2015 20:43
http://t.co/Hot6ceHGjI any good? #wecats
@CochraneUK
25 June 2015 20:43
RT @irishinneburg: .@sally_crowe Hazard ratio is a measure to compare time-to-event for two groups #wecats
@AmyPricePhD
25 June 2015 20:43
Sometimes ? asked in initial appraisal raise other one 2 look at great 2 do this in group like #WeCats https://t.co/Mw6uqnEAI0
@lisaburscheidt
25 June 2015 20:44
@UKCochraneCentr @sally_crowe I usually turn to wikipedia with my statistical #jargonbin questions https://t.co/7VAJdBrQyS #wecats
@Mental_Elf
25 June 2015 20:44
@irishinneburg @sally_crowe There's a nice overview of hazard ratios here: http://t.co/8CnGlxPZdr #wecats
@Pennyjhutch
25 June 2015 20:44
RT @CASPUK: QUESTION 3: Are the participants in the study all accounted for? Did any drop out and do we know why? #WeCATS http://t.co/ZL2B8…
@AgencyNurse
25 June 2015 20:44
RT @sally_crowe: any offers of a result for this trial in words or numbers? #wecats
@WeNursesToo
25 June 2015 20:44
RT @sally_crowe: any offers of a result for this trial in words or numbers? #wecats
@AgencyNurse
25 June 2015 20:44
RT @CASPUK: We suggest you look in the abstract for this information. The abstract should describe the results simply #WeCATS http://t.co/7…
@garry_tew
25 June 2015 20:44
RT @Mental_Elf: This paper gives you more detail on attention control groups: http://t.co/2rztRAfqsS #wecats
@sally_crowe
25 June 2015 20:44
so we have a result of 0.89 but it is within a range of 0.67 to 1.18 this is called a confidence interval #wecats
@WeNurses
25 June 2015 20:44
RT @CASPUK: We suggest you look in the abstract for this information. The abstract should describe the results simply #WeCATS http://t.co/7…
@CochraneUK
25 June 2015 20:44
RT @sally_crowe: so we have a result of 0.89 but it is within a range of 0.67 to 1.18 this is called a confidence interval #wecats
@WeNursesToo
25 June 2015 20:45
#phew #wecats https://t.co/MGLe74dEZb
@SteriuMD
25 June 2015 20:45
RT @sally_crowe: A trial design helps to address the other issues (apart from the intervention) that might affect the outcomes #wecats
@CochraneUK
25 June 2015 20:45
RT @Mental_Elf: @irishinneburg @sally_crowe There's a nice overview of hazard ratios here: http://t.co/8CnGlxPZdr #wecats
@jonnysoapbox
25 June 2015 20:46
#WeCATS what if the ratio was 1 https://t.co/Eq8Ywcm0Bh
@CochraneUK
25 June 2015 20:46
@CASPUK & hopefully be true to what you read later on in the paper! #wecats
@AgencyNurse
25 June 2015 20:46
I was lost on the meaning of the results - it seemed to give no clear "winner" ?? #WeCATS https://t.co/ia2gPsulHW
@htona_rus
25 June 2015 20:46
RT @CASPUK: Confidence Intervals give us the range within which the true size of effect (never exactly known) lies #WeCATS http://t.co/FgOT…
@WeNursesToo
25 June 2015 20:46
RT @Mental_Elf: @irishinneburg @sally_crowe There's a nice overview of hazard ratios here: http://t.co/8CnGlxPZdr #wecats
@HealthUKTD
25 June 2015 20:46
RT @CASPUK: We suggest you look in the abstract for this information. The abstract should describe the results simply #WeCATS http://t.co/7…
@CochraneUK
25 June 2015 20:46
@AgencyNurse I think this gets more interesting when we think about clinical significance #wecats
@sally_crowe
25 June 2015 20:47
within the range of results we have a 1 - and 1 is the line of treatment effect #wecats
@sally_crowe
25 June 2015 20:47
so if the result is not statistically significant - does it matter clinically? #wecats
@UCLanODP
25 June 2015 20:47
@Jo__Howe #wecats thanks Jo perfect
@AgencyNurse
25 June 2015 20:47
@UKCochraneCentr yes i can see that but still a little unsure of clinical significance here #WeCATS
@irishinneburg
25 June 2015 20:48
.@jonnysoapbox If the ratio was 1 the time-to-event would be exactly the same in both groups #wecats
@nursingSUni
25 June 2015 20:48
RT @PennyFawthrop: #WeCATS I'm learning that research papers need to be read several times for appraisals to be made. Going off first impre…
@CASPUK
25 June 2015 20:48
Here's the confidence interval slide again to back up @sally_crowe's point #WeCATS http://t.co/L6zQu3OM79
@AgencyNurse
25 June 2015 20:48
@nursingSUni @WeNurses we are over on #WeCATS tonights :)
@jonnysoapbox
25 June 2015 20:48
#WeCATS so maybe there is no clear winner. What if ratio was 1 https://t.co/8KabdaGyks
@PennyFawthrop
25 June 2015 20:48
@CASPUK the participant profile could be an indicator of why these deaths happened #WeCATS
@beetrooter
25 June 2015 20:48
RT @CASPUK: Here is a visual of what happens when people leave a clinical trial #WeCATS http://t.co/dlPgMXya6L
@nursingSUni
25 June 2015 20:48
@WeNurses #wecats but I'm very late @levylass sorry
@WeNurses
25 June 2015 20:48
RT @jonnysoapbox: #WeCATS so maybe there is no clear winner. What if ratio was 1 https://t.co/8KabdaGyks
@AmyPricePhD
25 June 2015 20:48
Could compare 2 prior population statistics 4 the type of patients? #WeCats https://t.co/AkI1Rv4Kgb
@nursingSUni
25 June 2015 20:48
RT @Mental_Elf: I'm jargon monitor at #WeCATS, but please help me out. If you notice any tricky language, stick it in the #JargonBin http:/…
@AgencyNurse
25 June 2015 20:49
@jonnysoapbox ahhh that makes sense #wecats
@CochraneUK
25 June 2015 20:49
RT @Mental_Elf: I'm jargon monitor at #WeCATS, but please help me out. If you notice any tricky language, stick it in the #JargonBin http:/…
@WeNurses
25 June 2015 20:49
RT @PennyFawthrop: @CASPUK the participant profile could be an indicator of why these deaths happened #WeCATS
@htona_rus
25 June 2015 20:49
RT @sally_crowe: @AgencyNurse @CASPUK yes the 'stickability' of this trial was good #wecats
@nursingSUni
25 June 2015 20:49
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@WeNurses
25 June 2015 20:49
RT @AmyPricePhD: Could compare 2 prior population statistics 4 the type of patients? #WeCats https://t.co/AkI1Rv4Kgb
@Jo__Howe
25 June 2015 20:49
RT @AmyPricePhD: Could compare 2 prior population statistics 4 the type of patients? #WeCats https://t.co/AkI1Rv4Kgb
@MentalhealthMSc
25 June 2015 20:49
RT @Mental_Elf: #WeCATS 8pm Appraising PREVENT RCT: #mindfulness-based cognitive therapy for #depression http://t.co/capK24t4i3 http://t.co…
@sally_crowe
25 June 2015 20:50
If mindfulness is as good as anti Ds for depression that is still quite effective? #wecats
@Jo__Howe
25 June 2015 20:50
@sally_crowe Yes - some people do not want can not take meds #wecats
@Katherine_JLA
25 June 2015 20:50
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@jonnysoapbox
25 June 2015 20:50
So the upper confidence limit is more than 1. What does that mean? #WeCATS
@Jo__Howe
25 June 2015 20:50
RT @jonnysoapbox: So the upper confidence limit is more than 1. What does that mean? #WeCATS
@AgencyNurse
25 June 2015 20:50
but i guess theres clinically as good and cost effectiveness and availability in practice ? #WeCATS https://t.co/capdNGMYcX
@sally_crowe
25 June 2015 20:51
@Jo__Howe indeed and that was the genesis of this study I think #wecats
@WeNurses
25 June 2015 20:51
RT @jonnysoapbox: So the upper confidence limit is more than 1. What does that mean? #WeCATS
@Mental_Elf
25 June 2015 20:51
@jonnysoapbox These results are not statistically significant #wecats
@lisaburscheidt
25 June 2015 20:51
@sally_crowe I would says yes, what do clinicians think? #wecats
@Jo__Howe
25 June 2015 20:51
@AgencyNurse offering a good alternative to Anti D's #wecats
@Mental_Elf
25 June 2015 20:51
The absence of a usual care or attention control group means that we can’t be sure that the effects of MBCT are specific to MBCT #wecats
@RuthyB27
25 June 2015 20:51
@sally_crowe #WeCATS ...sounds quite good to me....instead of taking pills
@beetrooter
25 June 2015 20:51
*waves* apologies for being so late. Am reading conversation as quick as possible to catch up! #WeCATS
@vankidzdoc
25 June 2015 20:51
RT @Mental_Elf: @irishinneburg @sally_crowe There's a nice overview of hazard ratios here: http://t.co/8CnGlxPZdr #wecats
@massagetherapy
25 June 2015 20:51
Learn more about critical apraisal of research #wecats via @WeNurses http://t.co/fmSmWphADj
@Jo__Howe
25 June 2015 20:51
@Mental_Elf Study has limitations for sure - no control group #wecats
@Jo__Howe
25 June 2015 20:52
RT @Mental_Elf: @irishinneburg @sally_crowe There's a nice overview of hazard ratios here: http://t.co/8CnGlxPZdr #wecats
@CochraneUK
25 June 2015 20:52
@AgencyNurse the results suggest that MBCT may be helpful, especially for those at high risk of relapse (again with the #!) #WeCATS
@CASPUK
25 June 2015 20:52
QUESTION 5: Were all of the important outcomes considered?...& if not, what is missing? #WeCATS http://t.co/TaNgwE2Jub
@AgencyNurse
25 June 2015 20:52
This paper seems to be pointing me in the direction of "pt centredness" its an option if pt comfy with this #WeCATS https://t.co/r6aTn3x0JU
@sally_crowe
25 June 2015 20:52
Finally lets dwell on the outcomes that were used - we know the primary outcome what about the rest? #wecats
@Mental_Elf
25 June 2015 20:52
@Jo__Howe This is good quality research though, compared to the other mindfulness studies that have been published recently #wecats
@WeNurses
25 June 2015 20:52
RT @CASPUK: QUESTION 5: Were all of the important outcomes considered?...& if not, what is missing? #WeCATS http://t.co/TaNgwE2Jub
@CochraneUK
25 June 2015 20:53
@UKCochraneCentr @AgencyNurse Table on p.8 is helpful for checking off the outcomes #wecats
@massagetherapy
25 June 2015 20:53
Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/t84qY10KDu"
@jonnysoapbox
25 June 2015 20:53
@Mental_Elf #WeCATS yes, and that it could be worse, we just not sure.
@Jo__Howe
25 June 2015 20:53
Does it state anywhere that patients themselves evaluated the trial? - patient involvement? #wecats
@rosieneall
25 June 2015 20:53
RT @CASPUK : QUESTION 5: Were all of the important outcomes considered?...& if not, what is missing? #WeCATS
@CochraneUK
25 June 2015 20:53
@Jo__Howe ooh I like that question! #wecats
@sally_crowe
25 June 2015 20:53
Who should determine the outcomes used in trials? #wecats
@AgencyNurse
25 June 2015 20:53
Runs to check table 8 #WeCATS https://t.co/SqtUv6Lz0n
@CochraneUK
25 June 2015 20:53
RT @Jo__Howe: Does it state anywhere that patients themselves evaluated the trial? - patient involvement? #wecats
@Jo__Howe
25 June 2015 20:54
@WeNurses @Mental_Elf agree - every study has limitations #wecats
@XMcVey
25 June 2015 20:54
RT @Mental_Elf: @irishinneburg @sally_crowe There's a nice overview of hazard ratios here: http://t.co/8CnGlxPZdr #wecats
@Mental_Elf
25 June 2015 20:54
@AgencyNurse This study is not sufficient evidence to say that MBCT is equivalent to antidepressants for recurrent depression #wecats
@AmyPricePhD
25 June 2015 20:54
Do we get 2 C Jargon bin results Use 4 glossary maybe #WeCats https://t.co/vXueLNb5cd
@UCLanODP
25 June 2015 20:54
@Mental_Elf #WeCATS what would have been usual care for these participants ?
@carlosneumoruiz
25 June 2015 20:54
RT @CASPUK: Confidence Intervals give us the range within which the true size of effect (never exactly known) lies #WeCATS http://t.co/FgOT…
@CASPUK
25 June 2015 20:54
Do you think the outcomes are important for people with depression, or for mental health professionals? #WeCATS http://t.co/r0P2jUHadF
@Jo__Howe
25 June 2015 20:54
@uclanodp @Mental_Elf Anti D's no treatment is my guess #wecats
@CochraneUK
25 June 2015 20:54
@AmyPricePhD we'll certainly do something with it. #Jargon Bin is important! #wecats
@sally_crowe
25 June 2015 20:54
Provocative slide coming up on outcomes! #wecats
@AmyPricePhD
25 June 2015 20:55
RT @UKCochraneCentr: @AmyPricePhD we'll certainly do something with it. #Jargon Bin is important! #wecats
@AgencyNurse
25 June 2015 20:55
So what would be needed ? #WeCATS https://t.co/CT3hV5sJJZ
@CochraneUK
25 June 2015 20:55
RT @uclanodp: @Mental_Elf #WeCATS what would have been usual care for these participants ?
@rosieneall
25 June 2015 20:55
I think all the important outcomes were considered #WeCATS
@htona_rus
25 June 2015 20:55
RT @sally_crowe: Who should determine the outcomes used in trials? #wecats
@lisaburscheidt
25 June 2015 20:55
@Jo__Howe I don't think they did - very good point Jo - we need more patient involvement in research. #wecats
@sally_crowe
25 June 2015 20:55
the outcomes section in this paper is quite well described page 3 right hand side #wecats
@AgencyNurse
25 June 2015 20:55
RT @lisaburscheidt: @Jo__Howe I don't think they did - very good point Jo - we need more patient involvement in research. #wecats
@WeNurses
25 June 2015 20:55
RT @lisaburscheidt: @Jo__Howe I don't think they did - very good point Jo - we need more patient involvement in research. #wecats
@Jo__Howe
25 June 2015 20:55
@CASPUK relapse may be too big a jump to aim for. Outcomes may be smaller - Ask the patients what are good outcomes for them #wecats
@JosefienMHF
25 June 2015 20:55
RT @beetrooter: *waves* apologies for being so late. Am reading conversation as quick as possible to catch up! #WeCATS
@Mental_Elf
25 June 2015 20:55
@AgencyNurse An RCT with a usual care group (or attention control group) being compared with MBCT #wecats
@AgencyNurse
25 June 2015 20:56
RT @sally_crowe: the outcomes section in this paper is quite well described page 3 right hand side #wecats
@CochraneUK
25 June 2015 20:56
@lisaburscheidt @Jo__Howe Hope @sally_crowe will share eyer fab work on this at the end - hot off the press too! #wecats
@sally_crowe
25 June 2015 20:56
@Jo__Howe @CASPUK excellent point Jo! #wecats
@WeNursesToo
25 June 2015 20:56
RT @Mental_Elf: @AgencyNurse An RCT with a usual care group (or attention control group) being compared with MBCT #wecats
@htona_rus
25 June 2015 20:56
RT @CASPUK: Do you think the outcomes are important for people with depression, or for mental health professionals? #WeCATS http://t.co/r0P…
@Jo__Howe
25 June 2015 20:56
patient involvement at trial design would mean better trials in long run - what patients what and need #wecats
@WeNursesToo
25 June 2015 20:56
RT @Jo__Howe: patient involvement at trial design would mean better trials in long run - what patients what and need #wecats
@CochraneUK
25 June 2015 20:56
@Jo__Howe @CASPUK yes yes yes! #wecats
@AmyPricePhD
25 June 2015 20:56
RT @AgencyNurse: Runs to check table 8 #WeCATS https://t.co/SqtUv6Lz0n
@rosieneall
25 June 2015 20:56
RT @CASPUK : Do you think the outcomes are important for people with depression, or for mental health professionals? #WeCATS
@nursingSUni
25 June 2015 20:57
@CASPUK #wecats I would suggest both? As mental health professionals want to work with clients for positive outcomes & for pts same
@briandavidearp
25 June 2015 20:57
RT @Mental_Elf: If you notice any jargon during #WeCATS pls help me chuck it in the #JargonBin & define it so everyone can join in http://t…
@JosefienMHF
25 June 2015 20:57
RT @CASPUK: Here is a structure (called PICO) to help you check if a treatment research question is clearly focused #WeCATS http://t.co/Elp…
@CochraneUK
25 June 2015 20:57
@beetrooter helloooo! You can catch up later too on the #WeNurses page #wecats
@lisaburscheidt
25 June 2015 20:57
@UKCochraneCentr @Jo__Howe @sally_crowe Ooh, exciting! #wecats
@nursingSUni
25 June 2015 20:57
RT @UKCochraneCentr: @Jo__Howe @CASPUK yes yes yes! #wecats
@sally_crowe
25 June 2015 20:57
overall we chose this paper as it is pretty well written has nice clear tables and figures and interesting! #wecats
@htona_rus
25 June 2015 20:57
RT @Jo__Howe: patient involvement at trial design would mean better trials in long run - what patients what and need #wecats
@Jo__Howe
25 June 2015 20:57
effective collaboration between researchers and patient groups must be the way forward #wecats
@gmckee89
25 June 2015 20:58
@Mental_Elf what is in the #jargonbin already? #WeCATS
@sally_crowe
25 June 2015 20:58
What did you think of it though?! #wecats
@rosieneall
25 June 2015 20:58
@CASPUK I don't think patients or health professionals were asked for what outcomes are important to them. Interesting... #WeCATS
@nursingSUni
25 June 2015 20:58
RT @Jo__Howe: patient involvement at trial design would mean better trials in long run - what patients what and need #wecats
@nursingSUni
25 June 2015 20:58
RT @lisaburscheidt: @Jo__Howe I don't think they did - very good point Jo - we need more patient involvement in research. #wecats
@AmyPricePhD
25 June 2015 20:58
#WeCats all people the intervention will affect include patients, they give early news 4 side effects, ease of use https://t.co/ebQ33EWEcv
@WeNursesToo
25 June 2015 20:58
What did others think of this paper ? #WeCATS https://t.co/ZJ6wjKCXMq
@nursingSUni
25 June 2015 20:58
RT @AmyPricePhD: Do we get 2 C Jargon bin results Use 4 glossary maybe #WeCats https://t.co/vXueLNb5cd
@HealthUKTD
25 June 2015 20:58
RT @lisaburscheidt: @Jo__Howe I don't think they did - very good point Jo - we need more patient involvement in research. #wecats
@irishinneburg
25 June 2015 20:58
.@Mental_Elf @AgencyNurse What would be necessary to decide about equivalence? #wecats
@Mental_Elf
25 June 2015 20:59
@gmckee89 #JargonBin is FULL: Intention to treat, blinding, hazard ratio, attention control group #wecats
@JosefienMHF
25 June 2015 20:59
RT @lisaburscheidt: @Jo__Howe I don't think they did - very good point Jo - we need more patient involvement in research. #wecats
@htona_rus
25 June 2015 20:59
@Jo__Howe and surely patient/public involvement would point towards a methodology that would minimise loss to follow-up? #wecats
@AgencyNurse
25 June 2015 20:59
@sally_crowe i think my mistake was not printing it out ... sounds simple but think it would have helped #WeCATS
@UoGMHNS
25 June 2015 20:59
RT @WeNurses: Tonights #WeCATS discussion is around this paper> http://t.co/RtljTB8fyN re mindfullness for recurrent depression & will be l…
@TaraJLamont
25 June 2015 20:59
@sally_crowe #wecats Looks like quite an impressive battery of secondary outcomes - lots of quality of life inc m/health ones
@United4Evidence
25 June 2015 20:59
Ditto! This is why need PATIENT-CENTERED outcomes research RT @UKCochraneCentr @Jo__Howe @CASPUK yes yes yes! #wecats
@Jo__Howe
25 June 2015 20:59
@htona_rus it certainly should! We as researchers need to get out of our ivory towers and start communicating! #wecats
@AgencyNurse
25 June 2015 20:59
@sally_crowe The tables really helped and i understood most of the language #WeCATS




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